Pubblicazioni su rivista

(2000-2004)

G.M Ledda-Columbano, M. Pibiri, R. Loi, A. Perra, H. Shinozuka, A. Columbano.
Early increase in cyclin-D1 expression and accelerated entry of mouse hepatocytes into S phase after administration of mitogen 1,4-Bis[2-3,5-dichloropyridyloxy)]benzene (TCPOBOP).
Am.J.Pathol, 156: 91-97, 2000

G.M Ledda-Columbano, M. Pibiri, A. Perra, R. Piga, R. Loi, M. Dore, H. Shinozuka, A Columbano.
Ciprofibrate and triiodothyronine do not suppress in vivo induction of placental glutathione-S-transferase espression in rat hepatocytes.
Cancer Lett, 151: 153-159, 2000

G.M Ledda-Columbano, A. Perra, R. Loi, M. Dore, H. Shinozuka, A. Columbano.
Cell proliferation induced by triiodothyronine in rat liver is associated with nodule regression and reduction of hepatocellular carcinomas.
Cancer Res., 60:603-609, 2000

M. Pibiri, G.M  Ledda-Columbano, C. Cossu, G. Simbula, M. Menegazzi, H. Shinozuka, A. Columbano.
Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3).
FASEB J 15:1006-1013, 2001

A. Columbano, G.M. Ledda-Columbano, M. Pibiri, D. Concas, J.K. Reddy, M.S. Rao.
Peroxisome proliferator-activated receptor- a/-/- mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene, a ligand of costitutive androstane receptor.
Hepatology 34:262-266, 2001

G.M. Ledda-Columbano, M. Pibiri, D. Concas, C. Cossu, M. Tripodi, A. Columbano
Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli
Hepatology, 36: 1098-1105, 2002

A. Columbano, G.M. Ledda-Columbano.
Mitogenesis by ligands of nuclear receptors: an attractive model for the study of the molecular mechanisms implicated in liver growth
Cell Death.Differ., 10: S19-S21, 2003

G.M. Ledda-Columbano, M. Pibiri, D. Concas, F. Molotzu, G. Simbula, C. Cossu, A. Columbano.
Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP.
Carcinogenesis, 24: 1059-1065, 2003

G.M. Ledda-Columbano, A. Perra, D. Concas, C. Cossu, F. Molotzu, C. Sartori, H. Shinozuka, A. Columbano.
Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma
Toxicol.Pathol. 31: 113-120, 2003

J. Locker, J. Tian, R. Carver, D. Concas, C. Cossu, G. M.Ledda-Columbano, A. Columbano.
A common set of immediate-early response genes in liver regeneration and hyperplasia
Hepatology, 38:314-325, 2003

G. Simbula, M.Pibiri, L. Sanna, C. Cossu, F. Molotzu, A. Columbano, G.M. Ledda-Columbano.
The peroxisome proliferator BR931 kills FaO cells by p53-dependent apoptosis.
Life Sci. 75:271-286, 2004