55) Synthesis and in vitro antitumoral activity of new 3,5-dicyanopyridine derivatives. Bioorg. Med. Chem., 15 (4), 1859-1867 (2007). Maria T. Cocco, Cenzo Congiu, Valentina Lilliu, Valentina Onnis

54) Synthesis, characterisation and insulin-mimetic activity of oxovanadium(IV) complexes with amidrazone derivatives. J. Inorg. Biochem. 101(1), 19-29 (2007). Maria Teresa Cocco, Valentina Onnis, Gustavo Ponticelli, Beate Meier, Dieter Rehder, Eugenio Garribba, Giovanni Micera

53) Effect of Lysine at C-Terminus of the Dmt-Tic Opioid Pharmacophore J. Med. Chem. 49 (18), 5610 – 5617 (2006) Gianfranco Balboni, Valentina Onnis, Cenzo Congiu, Margherita Zotti, Yusuke Sasaki, Akihiro Ambo, Sharon D. Bryant, Yunden Jinsmaa, Lawrence H. Lazarus, Claudio Trapella, Severo Salvadori

52)Amidrazones as Precursor of Biologically Active Compounds. Synthesis of Diaminopyrazoles for Evaluation of Anticancer Activity.Archiv. Der Pharmazie 339 (1), 7-13 (2006) Maria T. Cocco, Cenzo Congiu, Valentina Lilliu, Valentina Onnis

51) Synthesis and In Vitro Antitumoral Activity of New Hydrazinopyrimidine-5-carbonitrile Derivatives. Bioorg. Med. Chem., 14 (2), 366-372 (2006). Maria T. Cocco, Cenzo Congiu, Valentina Lilliu, Valentina Onnis

50) New Potential Anticancer Agents Based on Anthranilic Acid Scaffold. Synthesis and Evaluation of Biological Activity. J. Med. Chem., 48 (26) 8245-8252 (2005).

Cenzo Congiu, Maria T. Cocco, Valentina Lilliu, Valentina Onnis

49)Synthesis and antiproliferative activity of 2,6-Dibenzylamino-3,5-dicyanopyridines on human cancer cell lines

Eur. J. Med. Chem., 40 (12), 1365-1372 (2005). Maria T. Cocco, Cenzo Congiu, Valentina Lilliu, Valentina Onnis

48) In vitro antimycobacterial activity of newly synthesised S-alkylisothiosemicarbazone derivatives and synergistic interactions in combination with rifamycins against Mycobacterium avium. International Journal of Antimicrobial Agents 26 (1), 28-32 (2005). A. De Logu, M. Saddi, Valentina Onnis, C. Sanna, C. Congiu, R. Borgna, M. T. Cocco

47) Synthesis of new N-(2-(trifluoromethyl)pyridin-4-yl)anthranilic acid derivatives and their evaluation as anticancer agents. Bioorg. Med. Chem. Lett., 14 (23), 5787-5791 (2004).

Maria T. Cocco, Cenzo Congiu, Valentina Lilliu, Valentina Onnis

46) Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity. Bioorg. Med. Chem., 12 (15), 4169-4177 (2004). Maria T. Cocco, Cenzo Congiu, Valentina Onnis, Micaela Morelli, Vicente Felipo, Omar Cauli

45)Synthesis and Structural Studies of 3-(Acylamino)-4-amino-2,3-dihydro-2-iminothiazole-5-carboxylates             and 4-(Acylhydrazino)-2-aminothiazole-5-carboxylates. Heterocycles, 63, 259-270 (2004). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Sandra Ianelli

44)Synthesis of ibuprofen heterocyclic amides and investigation of their analgesic and toxicological properties Eur. J. Med. Chem., 38, 513-518 (2003). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Micaela Morelli,Omar Cauli

43)New bis(pyridyl)methane derivatives from 4-hydroxy-2-pyridones: synthesis and antitumoral activity Eur. J. Med. Chem., 38, 37-47 (2003). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis

42)Synthesis and In Vitro Antitumoral Activity of New N-Phenyl-3-pyrrolecarbothioamides. Bioorg. Med. Chem. 11, 495- 503 (2003). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis

41)Attività antimicobatterica di nuovi S-alchilisotiosemicarbazoni e potenziamento dell’attività di rifabutina, rifampicina e amikacina nei confronti di Mycobacterium avium. Giornale Italiano di Microbiologia Medica Odontoiatrica e Clinica, VI (2), 99-102, (2002). Alessandro De Logu, Valentina Onnis, Maria Luisa. Pellerano,             Maria Cristina Pusceddu, Barbara Saddi, Cenzo Congiu, Maria Antonietta Marcialis, Maria Teresa Cocco

40)Crystal and molecular structure of acetamidrazone derivatives. J. Chem. Crystallograph., 31, 149-154 (2001). Sandra Ianelli, G. Pelosi, Gustavo Ponticelli, Maria Teresa Cocco, Valentina Onnis

39)Synthesis and Antimycobacterial Activity of New S-Alkylisothiosemicarbazone Derivatives. Bioorg. Med. Chem., 10, 501-506 (2002). Maria Teresa Cocco, Cenzo Congiu,Valentina Onnis, Maria Luisa Pellerano, Alessandro De Logu

38)Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis. J. Antimicrob. Chemotherap. 49, 275-282 (2002). Alessandro De Logu, Valentina Onnis, Barbara Saddi, Cenzo Congiu, Maria Laura Schivo, Maria Teresa Cocco

37)Synthesis and antitumor evaluation of 6-thioxo-, 6-oxo- and 2,4-dioxopyrimidine derivatives. Farmaco, 56, 741-748 (2001). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Riccardo Piras

36)Synthesis, structure and cytotoxic activity of cobalt(II), nickel(II) and copper(II) chloride complexes with acetamidrazones. Transition Metal chemistry, 26, 24-27 (2001). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Gustavo Ponticelli, Sandra Ianelli, Francesco Cossu

35)Synthesis and Azannulation of pyridinylaminohexadienones. Chem. Pharm. Bull. 49 (6), 703-706 (2001) Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis

34)Transformation of 6-methylthiopyrimidines. Preparation of new pyrimidine derivatives and fused pyrimidines. J. Heterocyclic. Chem., 37, 707-710 (2000). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis

33)Synthesis and antitumour activity of 4-hydroxy-2-pyridone derivatives. Eur. J. Med. Chem., 35, 545-552 (2000). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis

32)Synthesis and antimycobacterial activity of some isonicotinoylhydrazones. Eur. J. Med. Chem. 34, 1071-1076 (1999). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Maria Cristina Pusceddu, Maria Laura Schivo, Alessandro De Logu

31)A Facile synthesis of 3,5-Diaminopyrazole-4-carbothioamides and 3,5-Diaminopyrazole-4-carboxylates. J. Heterocyclic Chem. 36, 1183-1188 (1999). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras

 

30)Palladium(II) and platinum(II), (IV) complexes of  2-aminopyrimidine derivatives. Transition Metal chemistry, 24, 370-372 (1999). Maria Teresa Cocco, Valentina Onnis, Gustavo Ponticelli, Antonio Spanu

29)Annulation of Functionalized Hexadienones as Efficient Regioselective Approach to N-Aryl-2-(trifluoromethyl)-4-pyridinamines. Tetrahedron Letters, 40, (23), 4407-4410 (1999). Maria Teresa Cocco, Cenzo congiu, Valentina Onnis

28)Palladium(II) and Platinum(II), (IV) Complexes of Acetamidrazones. Polyhedron, 17, 2065-2072 (1998)             Maria Teresa Cocco, Valentina Onnis, Gustavo Ponticelli, Antonio Spanu

27)A New and Efficient Synthesis of 1-(2H)Phthalazinones. Synthesis, 317-320 (1998). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras

26)Facile Synthesis of 2,2-Dimethylchromans by Mo(CO)₆ Catalyzed Reaction of Aryl Prenyl Ethers. Synthesis, 256-258 (1998). Angela Maria Bernard, Maria Teresa Cocco, Valentina Onnis, Pier Paolo Piras

25)A Study of the Stereochemistry of the dealkoxycarbonylation of some Sulfur-Substituted Cyclopropanes. Gazzetta Chimica Italiana, 127, 189-194 (1997). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras

24)Synthesis of New Fluorinated 1,5-Benzoxazepine Derivatives. J. Heterocyclic Chem., 34, 1347-1350 (1997). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras

23)Reaction of N¹-acylacetamidrazones with Trifluoroacetylvinyl Ethers. Synthesis of New Trifluoromethylpyridines. Journal of Heterocyclic Chemistry, 34, 1283-1290 (1997). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras.

22)Mo(CO)₆ Catalyzed One - Pot Conversion of Allyl Aryl Ethers to Dihydrobenzofurans. Synthesis, 41-43 (1997) Angela Maria Bernard, Maria Teresa Cocco, Valentina Onnis, Pier Paolo Piras.

21)New Trifluomethylated Pyridines from Functionalized N¹-Acylacetamidrazones. Journal of Heterocyclic Chemistry, 33, 1771-1773 (1996). Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras.

20)N¹-acyl-2-(ethoxycarbonyl)acetamidrazones as Starting Material for the Synthesis of Heterocycles. in Trends of Heterocyclic Chemistry 4, 13-23 (1995), ed. Research Trends, Council of Scientific Informations. Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis.

19)Propenethioamides in the Synthesis of Heterocyclic Systems. Synthesis of Pyrrole and 1,4-Thiazepine Derivatives. Journal of Heterocyclic Chemistry, 32, 1679-1682 (1995). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis.

18)Reactivity of N¹-Acylacetamidrazones towards Diethyl Acetilenedicarboxylate: Cyclization to Ethyl Pyrrole Acetates and 1-Acylaminopyridones. Heterocycles, 41, 1479-1490 (1995) Angela Maria Bernard, Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Pier Paolo Piras.

17)Synthesis of Trifluoromethylated Pyridinecarbonitriles. Journal of Heterocyclic Chemistry, 32, 543-545 (1995). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis.

16)Heterocyclization of Propenethioamides: A Direct Synthesis of 1,4-Thiazepine Ring Systems. Journal of Heterocyclic Chemistry, 32, 463-466 (1995). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis.

15)New Thioxopyrimidines. Synthesis and Evaluation for Antimicrobial Activity. Il Farmaco, 50, 73-76 (1995). Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis, Maria Laura Schivo, Alessandro De Logu 14)Synthesis of 2H-Pyrazolo[3,4-b]pyridin-3-oles via Cyclization of Pyrazolacrylonitriles. Journal of Heterocyclic Chemistry, 31, 925-928 (1994). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

13)Reaction of Enaminonitriles with Isocyanates. Synthesis of New 2-Oxo- and 6-Oxopyrimidines. Journal of Heterocyclic Chemistry, 31, 329-334 (1994). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

12)Synthesis and Antimicrobial Activity of New 3,5-Diaminoisothiazole Derivatives. Il Farmaco, 49, 137-140 (1994). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis, Maria Laura Schivo, Alessandro De Logu

11)Simple Synthesis of Polyfunctional Nitropyridines. Heterocycles, 36, 2829-2837 (1993) Maria Teresa Cocco, Cenzo Congiu, Valentina Onnis.

10)Convenient Synthesis of  4-Amino-7-(dialkylamino)pyrido[2,3-d]pyrimidines from Polysubstituted Pyridines Journal of Heterocyclic Chemistry, 30, 253-256 (1993). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

9)An Improved Procedure for the Preparation of Substituted Thiazoles. Synthesis, 199-201 (1993). Maria Teresa Cocco, Valentina Onnis.

8)Synthesis and Antimicrobial Activity of Some Pyrrole Derivatives V: 5-Aryl-3-ethoxycarbonyl-2-(4-substitutedpiperazino)pyrrole Derivatives. Il Farmaco, 47, 1395-1405 (1992). Maria Teresa Cocco, Valentina Onnis, Maria Laura Schivo, Alessandro De Logu

7)New Synthesis of 2-(1H)-Pyridone Derivatives. Journal of Heterocyclic Chemistry, 29, 1631-1634 (1992). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.6)1,2,4-Triazolo[4,3-c]pyrimidines From 4-Acylhydrazinopyrimidines Journal of Heterocyclic Chemistry, 29, 1341-1347 (1992). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

5)Synthesis of Some New 2(1H)-Pyridones from 3-Amino-3-(dialkylamino)propenenitriles Synthesis, 371-373 (1992). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

4)1-Acylaminoimidazoles, Synthesis and Antimicrobial Activity Il Farmaco, 47 (2), 229-238 (1992). Maria Teresa Cocco, Carlo Olla, Valentina Onnis, Maria Laura Schivo, Alessandro De Logu

3)Novel Reaction of Carbon Suboxide. Synthesis of 6-Amino-4-hydroxy-2(1H)-pyridone Derivatives. Journal of Heterocyclic Chemistry, 29, 237-239 (1992). Leonardo Bonsignore, Maria Teresa Cocco, Giuseppe Loy, Valentina Onnis.

2)Synthesis of  2-Amino-5-pyrimidinecarbonitrile Derivatives. Synthesis, 529-530 (1991). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.

1)Heterocyclization of Acetamidrazones I. Synthesis of 1,2,4-Triazolo[4,3-a]pyridines via Ring Closure of 6-(2-Acylhydrazino)pyridine Intermediates Journal of Heterocyclic Chemistry, 28, 797-800 (1991). Maria Teresa Cocco, Cenzo Congiu, Antonio Maccioni, Valentina Onnis.