M. Morelli, S. Fenu, G. Di Chiara:
Behavioural expression
of D1 receptor supersensitivity depends on previous stimulation of D2
receptors.
Life Science, Vol 40, pp 245-251, 1987.
M. Morelli, S. Fenu, G. Pomata, G. Di Chiara:
“Priming” phenomena in
the expression of D1 and D2 receptor supersensitivity.
In “Pharmacology
and functional regulation of dopaminergic neurons”, edited by P.M. Beart,
G.N. Woodruff and D.M. Jackson
Mac Millan, England, 1988
M. Morelli, S. Fenu, L. Garau, G. Di Chiara:
Time and dose dependence
of the “priming” of the expression of dopamine receptor supersensitivity.
Eur. J. Pharmacol., Vol 162, pp. 329-335, 1989.
M. Morelli, S. Fenu, G. Di Chiara:
Substantia nigra as a
site of origin of dopaminergic dependent motor syndromes induced by stimulation
of µ and δ opioid
receptors.
Brain Research, Vol 487, pp 120-130, 1989.
M. Morelli, S. Fenu, A. Cozzolino, G. Di Chiara:
The influence of
priming on the behavioral expression of dopamine receptor supersensitivity in
basal ganglia.
In “Basic,
clinical and therapeutic aspects of Alzheimer’s and Parkinson’s diseases”,
Vol I, edited by Nagatsu et al. Plenum Press, New York, 1990.
M. Morelli, G. De Montis, S. Fenu, A. Cozzolino, G. Di Chiara:
Priming of the
behavioral of dopamine-receptor supersensitivity in the basal ganglia:
pharmacological and biochemical studies.
In “The
basal ganglia III”, edited by G. Bernardi et al.Plenum Press, New York,
1990.
M. Morelli, S. Fenu, A. Cozzolino, G. Di Chiara:
Positive and negative
interactions in the behavioural expression of D1 and D2
receptor stimulation in a model of Parkinsonism: role of priming.
Neuroscience, Vol 42 No 1, pp 41-48, 1991.
M. Morelli, S. Fenu, A. Pinna, A. Cozzolino, G. Di Chiara:
Blockade of NMDA
receptors differentially affects D1 and D2 mediated
turning behavior in the 6-hydroxydopamine model of Parkinson.
Amino Acids, Vol 1, pp 205-213, 1991.
M. Morelli , S. Fenu , G. Di Chiara:
Blockade of
N-Methyl-D-aspartate receptors potentiates dopaminergic responses in the 6-OHDA
model of Parkinson: differential role of D1 and D2
receptors.
Neurochem. Int., 20 Suppl., pp 261-264, 1992
M. Morelli., S. Fenu , A. Pinna, G.
Di Chiara:
Opposite effects of
NMDA receptor blockade on dopaminergic D1 and D2-mediated
behavior in the 6-hydroxydopamine model of turning: relationship with c-fos
expression.
J. Pharmacol. Exp.
Therap.,Vol 260, pp
402-408, 1992
M. Morelli, S. Fenu, A. Cozzolino, A. Pinna, A. Carta and G. Di Chiara:
Blockade of muscarinic
receptors potentiated D1 dependent turning behavior and c-fos
expression in 6-hydroxydopamine lesioned rats while does not influence D2
mediated responses.
Neuroscience, Vol. 53, N° 3, pp 673-678, 1993
M. Morelli, A. Cozzolino, A.
Pinna, S. Fenu, A. Carta and G. Di
Chiara:
L-dopa stimulates in
dopamine denervated striatum by combined activation of D1 and D2
receptors.
Brain Research, Vol 623, pp 334-336, 1993.
M. Morelli, S. Fenu, A. Pinna, A. Cozzolino, A. Carta and G. Di Chiara:
"Priming" to
dopamine agonist-induced contralateral turning as a model of non-associative
sensitization to the expression of the post-synaptic dopamine message.
Behav. Pharmacology, Vol 4, pp 389-397, 1993
M. Morelli, S. Fenu A. Pinna and G. Di Chiara:
Adenosine a2
receptors interact negatively with dopamine D1 and D2
receptors in unilaterally 6-hydroxydopamine-lesioned rats.
Eur. J. Pharmacology,Vol 251, pp 21-25, 1994.
M. Morelli, A. Pinna, S. Fenu, A. Carta, A. Cozzolino and G.
Di Chiara:
Differential effect of
MK 801 and scopolamine on c-fos expression induced by l-dopa in the striatum of
6-hydroxydopamine lesioned rats.
Synapse, Vol 18, pp 288-293, 1994.
S. Fenu, A. Carta and M. Morelli:
Modulation of dopamine
D1-mediated turning behavior and striatal c-fos expression by the
substantia nigra.
Synapse, Vol 19, pp 233-240, 1995.
S. Fenu, A. Carta and M. Morelli:
Intranigral injections
of glutamate antagonists modulate dopamine D1-mediated turning
behavior and striatal c-fos expression.
J. Neural. Transm., Vol 45, pp 75-81, 1995
M. Morelli, S. Fenu, A. Carta and G. Di Chiara:
Effect of MK 801 on
priming of D1-dependent contralateral turning and its relationship
to c-fos expression in the rat caudate-putamen.
Behav. Brain Research. Vol 79, pp 93-100, 1996.
S. Fenu, A. Pinna, E. Ongini, M. Morelli :
Adenosine A2A
receptor antagonism potentiates L-dopa-induced turning behaviour and c-fos
expression in 6-hydroxydopamine-lesioned rats.
Eur. J. Pharm. Vol 321, pp 143-147, 1997.
S. Fenu, M. Morelli:
Motor stimulants
effects of caffeine in 6-hydroxydopamine lesioned rats are dEpendent on
previous stimulation of dopamine receptors: different role of D1 and
D2 receptors.
Eur. J. Neuroscience Vol 10, pp 1878-1884, 1998.
M. Morelli, S. Fenu:
ROLE OF DOPAMINE RECEPTORS IN THE INDUCTION AND EXPRESSION
OF ROTATIONAL BEHAVIOR INDUCED BY CAFFEINE IN 6-HYDROXYDOPAMINE-LESIONED RATS.
Drug Development
Research, Vol 45,
pp 373-378, 1998
E. Acquas, S.
Fenu, P. Loddo, G. Di Chiara:
A
WITHIN-SUBJECTS MICRODIALYSIS-BEHAVIOURAL STUDY OF THE ROLE OF STRIATAL
ACETYLCHOLINE IN D1-DEPENDENT TURNING.
Behavioral Brain Research Vol 103, pp
219-228, 1999
G. Di Chiara, G. Tanda, V. Bassareo, F. Pontieri,
E. Acquas, S. Fenu, C. Cadoni, E.
Carboni:
DRUG ADDICTION
AS A DISORDER OF ASSOCIATIVE LEARNING: ROLE OF NUCLEUS ACCUMBENS SHELL/EXTENDED
AMYGDALA DOPAMINE.
Annals of the New York Academy of Sciences, Vol 877, pp
461-485, 1999
S. Fenu, O. Cauli, M. Morelli:
CROSS-SENSITIZATION BETWEEN THE MOTOR
ACTIVATING EFFECTS OF BROMOCRIPTINE AND CAFFEINE: ROLE OF ADENOSINE A2A
RECEPTORS.
Behav. Brain Research,
Vol 114, pp 97-105,
2000
A Pinna, S. Fenu, M. Morelli:
MOTOR STIMULANT EFFECTS OF THE ADENOSINE A2A
RECEPTOR ANTAGONIST SCH 58261 DO NOT DEVELOP TOLERANCE AFTER REPEATED
TREATMENTS IN 6-HYDROXYDOPAMINE-LESIONED RATS.
SYNAPSE, Vol: 39, pp 233-238,
2001.
A. Carta, S. Fenu, M. Morelli:
ALTERATIONS
ON GAD67, DYNORPHIN AND ENKEPHALIN mRNA IN STRIATAL OUTPUT NEURONS FOLLOWING
PRIMING IN THE 6-OHDA MODEL OF PARKINSON’S DISEASE.
Neurological Sciences, Vol 22 (1), pp 59-60, 2001
S.Fenu, E.
Acquas, G. Di Chiara:
ROLE OF
ACETYLCHOLINE ON DOPAMINE D1 RECEPTOR AGONIST-INDUCED TURNING
BEHAVIOUR IN 6-HYDROXYDOPAMINE LESIONED RATS: A MICRODIALYSIS/BEHAVIOURAL
STUDY.
Neurological Sciences, Vol 22 (1), pp 63-64, 2001
S.Fenu, V.
Bassareo, G. Di Chiara:
A ROLE
FOR DOPAMINE D1 RECEPTORS OF THE NUCLEUS ACCUMBENS SHELL IN
CONDITIONED TASTE AVERSION.
Journal of Neuroscience, Vol 21(17), pp 6897-6904, 2001
S.Fenu, G. Di Chiara :
FACILITATION
OF CONDITIONED TASTE AVERSION LEARNING BY SYSTEMIC AMPHATAMINE: ROLE OF NUCLEUS
ACCUMBENS SHELL DOPAMINE D1 RECEPTORS.
European J Neuroscience, Vol 18, pp 2025-2039, 2003
A.R. Carta, S. Fenu, P. Pala, E. Tronci, M. Morelli.
SELECTIVE
MODIFICATIONS IN GAD67 mRNA LEVELS IN STRIATONIGRAL AND STRIATOPALLIDAL
PATHWAYS CORRELATE TO DOPAMINE AGONIST PRIMING IN 6-HYDROXYDOPAMINE-LESIONED
RATS.
European J Neuroscience, Vol 18, pp 2563-2572, 2003
N. Simola, S. Fenu, P.G. Baraldi, M.A. Tabrizi, M.
Morelli.
BLOCKADE OF
ADENOSINE A2A RECEPTORS ANTAGONIZES PARKINSONIAN
TREMOR IN THE RAT TACRINE MODEL BY AN ACTION ON SPECIFIC STRIATAL
REGIONS
Experimental Neurology in press, 2004
G. Di Chiara, V. Bassareo, S. Fenu, M. A. De Luca, L.
Spina, C. Cadoni, E. Acquas, E. Carboni
DOPAMINE
AND DRUG ADDICTION: THE NUCLEUS ACCUMBENS SHELL CONNECTION
Neuropharmacology,
in press, 2004